New AURORAI (Horizon Europe): PPKE leads outbreak-prediction modelling →

High Performance Computing Research Group

High-Level Algorithms, Peak Hardware Performance, Real-World Impact

We design domain-specific abstractions and performance-portable software for modern heterogeneous systems. Our work connects algorithm theory, compiler/runtime design, and production-scale applications in aerospace, public health, medical imaging, and more.

Flagship project · Horizon Europe

AURORAI

Advancing Pandemic Preparedness and Response through High-Quality Data and AI

AURORAI strengthens the EU's capacity to act swiftly and effectively against future pandemics, including unknown pathogens (“Disease X”), by building explainable, ethical and fast-learning AI tools on high-quality, trustworthy data.

PPKE leads Work Package 4. Building on our GPU-accelerated agent-based epidemic simulator PanSim, we are developing the behaviour-aware, AI-enhanced population modelling at the core of the project's Early Warning and Outbreaks Prediction (EW-OP) tool, with Hungary as the first national pilot.

WP4 lead

PPKE's role: behaviour-aware, AI-enhanced population modelling

48 months

From 1 September 2026

14 organisations

From 10 countries, coordinated by IDENER (Spain)

5 innovations

Data, Disease X modelling, early warning, decision support, Knowledge Hub

Institutional PI at PPKE: Prof. István Reguly

36

6 BSc, 27 MSc, and 3 PhD theses completed

12

Student Research Competition (TDK) projects completed with HPC lab mentoring

6

Award-winning National Student Research Competition (OTDK) works

Institutional Identity

The HPC Group operates at Pázmány Péter Catholic University, Faculty of Information Technology and Bionics (PPKE ITK), where interdisciplinary engineering and life-science research are intentionally integrated.

Convergence by Design

PPKE ITK was founded on a convergence model linking computer engineering, electronics, and bionics. This gives our group a naturally diverse application base for advanced simulation and data analysis.

Flat Research Organization

With 33 research groups in a collaborative environment, we can rapidly form cross-disciplinary teams around complex computational challenges.

Leadership

The group is led by Dr. István Reguly, full Professor and Vice Dean for International Affairs, with expertise in high-performance computing, CFD, and domain-specific language design. He is the institutional PI of PPKE in the Horizon Europe project AURORAI.

Core Research Programs

We raise abstraction for domain scientists while retaining efficient mapping to modern hardware through active-library DSL frameworks and automated backend optimization.

OP2 for Unstructured Meshes

Decoupled access-execute modeling with sets, datasets, and mappings. Backends include OpenMP, CUDA, HIP/SYCL, and MPI for distributed systems.

OPS for Structured Multi-block Grids

Code-generation driven stencil optimization with runtime loop tiling for memory-bound workloads, delivering near hand-tuned performance.

Epidemic Modelling at Scale

PanSim, our GPU/CPU agent-based epidemic microsimulator, is being scaled from city to national level within AURORAI.

Application-oriented Research

We collaborate with a wide range of engineers, scientists, and domain experts to speed up applications, unlocking new insights and capabilities.

Socio-Economic and Scientific Impact

Our frameworks are deployed in high-value domains where performance and correctness directly affect policy, engineering, and medicine.

Public Health

PanSim enabled broad scenario testing for COVID-19 interventions including mobility, masking, and school policies under uncertainty. In AURORAI it becomes the core of a national-scale early warning and outbreak prediction tool.

Aerospace CFD

Through collaborations including Rolls-Royce, the Universities of Warwick, Southampton, and Nottingham, our methods support the modeling of airflow, turbulence, combustion, and more.

Medical Imaging & Bioinformatics

GPU-accelerated diffusion MRI and whole-cell simulation projects provide scalable computational tools for modern neuroimaging and personalized medicine research.

Build the Next Generation of Scientific Software

We welcome MSc, PhD, and postdoctoral researchers interested in heterogeneous computing, DSLs, AI-enhanced epidemic modelling, and high-impact interdisciplinary applications.